Abstract
A paper recently published in Science reports that adenosine deaminase acting on RNA 1-dependent adenosine-to-inosine editing marks endogenous double strand RNA as self and prevents their immune recognition by cytosolic RNA sensor MDA5.
MeSH terms
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Adenosine Deaminase / metabolism*
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Animals
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DEAD-box RNA Helicases / metabolism*
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Embryo Loss / genetics*
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RNA Editing*
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RNA, Double-Stranded / metabolism*
Substances
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RNA, Double-Stranded
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Adenosine Deaminase
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DEAD-box RNA Helicases