A TICT based NIR-fluorescent probe for human serum albumin: a pre-clinical diagnosis in blood serum

Chem Commun (Camb). 2016 Jan 21;52(6):1182-5. doi: 10.1039/c5cc08217j.


A TICT based NIR-fluorescent probe 3 has been designed and synthesized, which selectively detects HSA with fluorescence enhancement in blood plasma with a detection limit of 11 nM among the various proteins, nucleotides and thiols tested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Diagnosis*
  • Fluorescent Dyes / chemistry*
  • Humans
  • Limit of Detection
  • Serum Albumin / analysis*
  • Spectroscopy, Near-Infrared / methods*


  • Fluorescent Dyes
  • Serum Albumin