Anterior chamber depth studies

J Cataract Refract Surg. 2015 Sep;41(9):1898-904. doi: 10.1016/j.jcrs.2015.10.010.


Purpose: To compare the anterior chamber depth (ACD; corneal epithelium to lens) using 3 modalities and compare the change 1 day and 3 months postoperatively.

Setting: Private practice, Santa Monica, California, USA.

Design: Nonrandomized prospective series.

Methods: The mean optical pachymetry and immersion ultrasound (US) of the ACD and partial coherence interferometry (PCI) were measured. Optical pachymetry ACD was measured in 675 eyes postoperatively at 1 day and 3 months.

Results: The optical pachymetry ACD in 492 eyes was 3.17 mm ± 0.42 (SD); by immersion US, it was 2.99 ± 0.51 mm (0.18 mm deeper; P < .0001). In 178 eyes, the optical pachymetry ACD was 3.23 ± 0.45 mm; the PCI was 3.19 ± 0.48 mm (0.04 mm deeper), which was not statistically different (P > .05). In 675 eyes, optical pachymetry ACD preoperatively was 3.19 ± 0.40 mm. The postoperative 1-day optical pachymetry ACD was 4.35 ± 0.35 mm with a mean refractive error of -0.30 diopter (D); the final 3-month optical pachymetry ACD was 4.47 ± 0.31 mm, with a mean refractive error of -0.07 D (P < .0001). This is a mean intraocular lens (IOL) position shift of +0.12 mm posteriorly; the +0.23 D change represents a ratio of 1.92 D/mm of IOL axial movement.

Conclusions: The PCI ACD was comparable with optical pachymetry, but careful immersion US led to a 0.18 mm shorter ACD reading that cannot be corrected by sound velocity. The posterior capsule contracted and moved the IOL posteriorly 0.12 mm, resulting in 0.23 D hyperopic shift.

Financial disclosure: Dr. Hoffer owns the registered trademark name "Hoffer(®)" and receives royalties for its commercial use from Alcon Laboratories, Inc., Appasamy Associates, Carl Zeiss Meditec AG, DGH Technology, Inc., Ellex iScience, Inc., Haag-Streit AG, Nidek Co., Ltd., Tomey Corp., Topcon Medical Systems, Inc., and Ziemer USA, Inc., as well as royalties from Slack, Inc. for the textbook IOL Power. Neither author has a financial or proprietary interest in any material or method mentioned.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anterior Chamber / pathology*
  • Biometry / instrumentation*
  • Corneal Pachymetry / instrumentation
  • Female
  • Humans
  • Interferometry / instrumentation
  • Lens Implantation, Intraocular*
  • Lenses, Intraocular*
  • Male
  • Microscopy, Acoustic / instrumentation
  • Middle Aged
  • Optics and Photonics
  • Phacoemulsification*
  • Postoperative Period
  • Prospective Studies