Long-term postoperative outcomes after bilateral congenital cataract surgery in eyes with microphthalmos

J Cataract Refract Surg. 2015 Sep;41(9):1910-8. doi: 10.1016/j.jcrs.2015.10.005.


Purpose: To evaluate the long-term impact of bilateral cataract surgery on postoperative complications, influence of age at surgery on the pattern of axial growth and central corneal thickness (CCT), and visual and orthoptic assessment in microphthalmic eyes.

Setting: Iladevi Cataract and IOL Research Centre, Ahmedabad, India.

Design: Prospective longitudinal study.

Methods: This study assessed children with microphthalmos who had bilateral congenital cataract surgery. Microphthalmos was defined as an eye that has an axial length (AL) that was 2 standard deviations smaller than what is normally expected at that age. All eyes were left aphakic. One of the 2 eyes was randomly selected for analysis. Postoperative complications, AL, CCT, and visual acuity were documented.

Results: This study included 72 eys of 36 children. The mean age of the patients was 4.8 months ± 6.2 (SD) (range 0.5 to 15 months). Postoperative complications included secondary glaucoma (11/36, 30.6%), visual axis obscuration (4/36, 11.1%), and posterior synechiae (10/36, 27.8%). A significant rate of change was observed in axial growth up to 4 years and in CCT up to 3 years postoperatively. When age at the time of surgery was correlated with the profile of the rate of change in AL and CCT at 1 month and 1, 2, and 4 years, statistically significant differences in AL and CCT at all timepoints were found. Loss of vision after surgery occurred in 2 eyes.

Conclusion: After early surgical intervention, an acceptable rate of serious postoperative complications and good visual outcomes were obtained in microphthalmic eyes.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

MeSH terms

  • Aphakia, Postcataract / etiology
  • Aphakia, Postcataract / physiopathology
  • Axial Length, Eye / pathology
  • Cataract / congenital*
  • Cataract / physiopathology
  • Cataract Extraction / methods*
  • Cornea / pathology
  • Corneal Pachymetry
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Intraocular Pressure / physiology
  • Male
  • Microphthalmos / physiopathology
  • Microphthalmos / surgery*
  • Postoperative Complications*
  • Prospective Studies
  • Treatment Outcome
  • Visual Acuity / physiology