International cooperation to improve access to and sustain effectiveness of antimicrobials

Lancet. 2016 Jan 16;387(10015):296-307. doi: 10.1016/S0140-6736(15)00470-5. Epub 2015 Nov 18.


Securing access to effective antimicrobials is one of the greatest challenges today. Until now, efforts to address this issue have been isolated and uncoordinated, with little focus on sustainable and international solutions. Global collective action is necessary to improve access to life-saving antimicrobials, conserving them, and ensuring continued innovation. Access, conservation, and innovation are beneficial when achieved independently, but much more effective and sustainable if implemented in concert within and across countries. WHO alone will not be able to drive these actions. It will require a multisector response (including the health, agriculture, and veterinary sectors), global coordination, and financing mechanisms with sufficient mandates, authority, resources, and power. Fortunately, securing access to effective antimicrobials has finally gained a place on the global political agenda, and we call on policy makers to develop, endorse, and finance new global institutional arrangements that can ensure robust implementation and bold collective action.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / supply & distribution
  • Anti-Infective Agents / therapeutic use*
  • Drug Resistance, Microbial*
  • Health Policy
  • Health Services Accessibility
  • Humans
  • Infection Control / methods
  • International Cooperation*
  • Population Surveillance


  • Anti-Infective Agents