Can Helminth Infection Reverse Microbial Dysbiosis?

Trends Parasitol. 2015 Nov;31(11):534-535. doi: 10.1016/


There is growing interest in treating inflammatory conditions with helminth infection. Recently, Loukas and colleagues have reported promising results from using experimental hookworm infection to reduce gluten sensitivity in celiac disease patients. Analysis of microbiota samples from the trial is contributing to our understanding of the complexity underlying helminth–microbiota–host relationships.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Ancylostomatoidea*
  • Animals
  • Biodiversity*
  • Celiac Disease / etiology*
  • Gastrointestinal Microbiome*
  • Glutens / metabolism*
  • Hookworm Infections*
  • Humans


  • Glutens