Managing nut-induced anaphylaxis: challenges and solutions

J Asthma Allergy. 2015 Oct 29:8:115-23. doi: 10.2147/JAA.S89121. eCollection 2015.


The prevalence of peanut and tree nut allergy in the USA has increased, especially in the pediatric population. Nut allergy remains the leading cause of fatal anaphylactic reactions. Management of anaphylaxis includes not only treatment of symptoms during a reaction, but strict dietary avoidance and education on potential situations, which may place the patient at high risk for accidental exposure. Cross-reactivity between various nuts along with various cross-contamination sources should be discussed with all nut-allergic individuals. Exciting research continues to emerge on other potential treatments for patients allergic to nuts, including allergen immunotherapy. Results of such interventions have been encouraging, though further studies are needed regarding safety and long-term outcomes before these can be applied to clinical practice.

Keywords: anaphylaxis; avoidance; cross-reactivity; immunotherapy; peanut; tree nut.

Publication types

  • Review