ESCRT Filaments as Spiral Springs

Lars-Anders Carlson; Qing-Tao Shen; Mark Remec Pavlin; James H Hurley

doi:10.1016/j.devcel.2015.11.007

ESCRT Filaments as Spiral Springs

Dev Cell. 2015 Nov 23;35(4):397-8. doi: 10.1016/j.devcel.2015.11.007.

Authors

Lars-Anders Carlson¹, Qing-Tao Shen¹, Mark Remec Pavlin², James H Hurley³

Affiliations

¹ Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA.
² Biophysics Graduate Program, University of California, Berkeley, Berkeley, CA 94720, USA.
³ Department of Molecular and Cell Biology and California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics & Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. Electronic address: jimhurley@berkeley.edu.

PMID: 26609952
DOI: 10.1016/j.devcel.2015.11.007

Abstract

In a recent issue of Cell, Chiaruttini et al. (2015) reveal the mechanical properties of the mysterious spiral filaments formed by the yeast ESCRT-III protein Snf7. The spirals are shown to be springs whose bending drives membrane deformation and perhaps membrane scission.

Publication types

Comment

MeSH terms

Endosomal Sorting Complexes Required for Transport / chemistry*
Endosomal Sorting Complexes Required for Transport / ultrastructure*
Lipid Bilayers / chemistry*
Models, Molecular*
Yeasts / metabolism*

Substances

Endosomal Sorting Complexes Required for Transport
Lipid Bilayers