ESCRT Filaments as Spiral Springs

Dev Cell. 2015 Nov 23;35(4):397-8. doi: 10.1016/j.devcel.2015.11.007.

Abstract

In a recent issue of Cell, Chiaruttini et al. (2015) reveal the mechanical properties of the mysterious spiral filaments formed by the yeast ESCRT-III protein Snf7. The spirals are shown to be springs whose bending drives membrane deformation and perhaps membrane scission.

Publication types

  • Comment

MeSH terms

  • Endosomal Sorting Complexes Required for Transport / chemistry*
  • Endosomal Sorting Complexes Required for Transport / ultrastructure*
  • Lipid Bilayers / chemistry*
  • Models, Molecular*
  • Yeasts / metabolism*

Substances

  • Endosomal Sorting Complexes Required for Transport
  • Lipid Bilayers