Keeping Order in Anaphase

Dev Cell. 2015 Nov 23;35(4):403-4. doi: 10.1016/j.devcel.2015.11.011.

Abstract

The critical components of chromosome segregation machinery are well established, but how they orchestrate the relative order of events during mitosis remains unclear. Kamenz et al. (2015) now report in Molecular Cell quantitative data suggesting competing networks and adaptive thresholds in the control of mitotic exit by the anaphase-promoting complex.

Publication types

  • Comment

MeSH terms

  • Anaphase / physiology*
  • Cyclin B / metabolism*
  • Models, Biological*
  • Schizosaccharomyces / metabolism*
  • Schizosaccharomyces pombe Proteins / metabolism*

Substances

  • Cyclin B
  • Schizosaccharomyces pombe Proteins