18-FDG PET/ CT Scan in the Diagnosis and Follow-up of Chronic Q fever Aortic Valve Endocarditis

Heart Lung Circ. 2016 Feb;25(2):e17-20. doi: 10.1016/j.hlc.2015.09.007. Epub 2015 Oct 21.


Chronic Q fever endocarditis is a rare but important infection associated with risk of morbidity and mortality. Echocardiography rarely visualises the vegetative lesion. We describe the first Australian report of chronic Q fever aortic valve endocarditis confirmed with the use of 18 -FDG PET/ CT scan. Following valvular replacement, the patient had ongoing high serological titres despite active treatment and he was managed with yearly serial PET/ CT scan to confirm the absence of active infection. The utility of serial PET /CT scan imaging as a follow-up management strategy has not been described in the literature previously and should be investigated further.

Keywords: 18 FDG; Coxiella; Endocarditis; Fluorodeoxyglucose; Positron Emission Topography; Q fever.

Publication types

  • Case Reports

MeSH terms

  • Aortic Valve / diagnostic imaging*
  • Endocarditis, Bacterial / diagnostic imaging*
  • Endocarditis, Bacterial / drug therapy
  • Follow-Up Studies
  • Glucose-6-Phosphate / administration & dosage
  • Glucose-6-Phosphate / analogs & derivatives*
  • Heart Valve Diseases / diagnostic imaging*
  • Heart Valve Diseases / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Positron-Emission Tomography*
  • Q Fever / diagnostic imaging*
  • Q Fever / drug therapy
  • Tomography, X-Ray Computed*


  • 2-fluoro-2-deoxyglucose-6-phosphate
  • Glucose-6-Phosphate