Minimally Invasive Parathyroidectomy Versus Bilateral Neck Exploration for Primary Hyperparathyroidism

Surg Oncol Clin N Am. 2016 Jan;25(1):103-18. doi: 10.1016/j.soc.2015.08.012.


Primary hyperparathyroidism is a disease that is caused by excess parathyroid hormone (PTH) secretion from 1 or more of the parathyroid glands. Surgery is the only cure. Traditional surgical management consists of a 4-gland cervical exploration. Development of imaging specific to identification of parathyroid glands and application of the rapid PTH assay to operative management have made more minimal exploration possible. There are distinct advantages and disadvantages of minimally invasive parathyroidectomy (MIP) and bilateral neck exploration (BNE). The advantages of MIP seem to outweigh those of BNE, and MIP has replaced BNE as the operation of choice by many surgeons.

Keywords: Intraoperative parathyroid hormone; Minimally invasive parathyroidectomy; Parathyroidectomy; Primary hyperparathyroidism; Surgery.

Publication types

  • Review

MeSH terms

  • Diagnostic Imaging / methods
  • Humans
  • Hyperparathyroidism, Primary / surgery*
  • Minimally Invasive Surgical Procedures / methods*
  • Neck Dissection / methods*
  • Parathyroidectomy / methods*