Functional MR Imaging Techniques in Oncology in the Era of Personalized Medicine

Magn Reson Imaging Clin N Am. 2016 Feb;24(1):1-10. doi: 10.1016/j.mric.2015.08.001. Epub 2015 Sep 26.

Abstract

DW and DCE MR imaging contribute significantly to diagnosis, treatment planning, response assessment, and prognosis in personalized cancer medicine. Nevertheless, the need for further standardization of these techniques needs to be addressed. Whole-body DW MR imaging is an exciting field; however, future studies need to investigate in more depth the biologic significance of the findings depicted, their prognostic relevance, and cost-effectiveness in comparison with MDCT and PET/CT. New MR imaging probes, such as targeted or activatable contrast agents and dynamic nuclear hyperpolarization, show great promise to further improve the care of patients with cancer in the near future.

Keywords: DCE; DNP; DWI; Hepatobiliary contrast agent; MRS; SPIO.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism*
  • Humans
  • Magnetic Resonance Imaging / trends*
  • Magnetic Resonance Spectroscopy / methods*
  • Medical Oncology / trends
  • Molecular Imaging / trends*
  • Neoplasms / diagnosis*
  • Neoplasms / metabolism
  • Precision Medicine / trends*

Substances

  • Biomarkers, Tumor