Multiparametric MR Imaging of Breast Cancer

Magn Reson Imaging Clin N Am. 2016 Feb;24(1):223-238. doi: 10.1016/j.mric.2015.08.012.


Breast MR imaging has increased in popularity over the past 2 decades due to evidence of its high sensitivity for cancer detection. Current clinical MR imaging approaches rely on the use of a dynamic contrast-enhanced acquisition that facilitates morphologic and semiquantitative kinetic assessments of breast lesions. The use of more functional and quantitative parameters holds promise to broaden the utility of MR imaging and improve its specificity. Because of wide variations in approaches for measuring these parameters and the considerable technical challenges, robust multicenter data supporting their routine use are not yet available, limiting current applications of many of these tools to research purposes.

Keywords: Breast cancer; Diffusion-weighted imaging; Dynamic contrast enhanced; Magnetic resonance spectroscopy; Multiparametric breast MR imaging.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism*
  • Breast Neoplasms / diagnosis*
  • Contrast Media / pharmacokinetics*
  • Diffusion Magnetic Resonance Imaging / trends*
  • Humans
  • Magnetic Resonance Angiography / trends*
  • Magnetic Resonance Spectroscopy / methods
  • Molecular Imaging / trends
  • Multimodal Imaging / trends*


  • Biomarkers, Tumor
  • Contrast Media