Abstract
A new antibacterial antibiotic, designated LL-E19085 alpha, was isolated from the fermentation broth of an actinomycete strain. Based on cultural, physiological, morphological and chemical characteristics, culture LL-E19085 was identified as a new subspecies of Micromonospora citrea. Antibiotic LL-E19085 alpha demonstrated potent activity against a spectrum of Gram-positive aerobic and anaerobic bacteria.
MeSH terms
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Animals
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Anti-Bacterial Agents / biosynthesis*
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Bacteria / drug effects*
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Culture Media
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Fermentation
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Mice
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Micromonospora / classification
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Micromonospora / growth & development
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Micromonospora / metabolism*
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Micromonospora / ultrastructure
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Microscopy, Electron
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Molecular Structure
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Oxazoles / biosynthesis
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Oxazoles / pharmacology
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Oxazoles / therapeutic use
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Spores, Bacterial / ultrastructure
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Streptococcal Infections / drug therapy*
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Streptococcus pyogenes / drug effects
Substances
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Anti-Bacterial Agents
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Culture Media
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Oxazoles
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citreamicin alpha