Minimally Invasive Neurosurgery for Epilepsy Using Stereotactic MRI Guidance

S Kathleen Bandt; Eric C Leuthardt

doi:10.1016/j.nec.2015.08.005

Minimally Invasive Neurosurgery for Epilepsy Using Stereotactic MRI Guidance

Neurosurg Clin N Am. 2016 Jan;27(1):51-8. doi: 10.1016/j.nec.2015.08.005. Epub 2015 Oct 24.

Authors

S Kathleen Bandt¹, Eric C Leuthardt²

Affiliations

¹ Department of Neurological Surgery, Washington University School of Medicine, Campus Box 8057, 660 South Euclid Avenue, St Louis, MO 63110, USA. Electronic address: skbandt@gmail.com.
² Department of Neurological Surgery, Washington University School of Medicine, Campus Box 8057, 660 South Euclid Avenue, St Louis, MO 63110, USA; Department of Biomedical Engineering, Washington University, St Louis, MO 63110, USA; Center for Innovation in Neuroscience and Technology, Washington University School of Medicine, St Louis, MO 63110, USA.

PMID: 26615107
DOI: 10.1016/j.nec.2015.08.005

Abstract

Medically refractory epilepsy is associated with significant morbidity and mortality. Surgery is a safe and effective option for some patients, however the opportunity exists to develop less invasive and more effective surgical options. To this end, multiple minimally invasive, image-guided techniques have been applied to the treatment of epilepsy. These techniques can be divided into thermoablative and disconnective techniques. Each has been described in the treatment of epilepsy only in small case series. Larger series and longer follow up periods will determine each option's place in the surgical armamentarium for the treatment of refractory epilepsy but early results are promising.

Keywords: Epilepsy surgery; Laser ablation; Medically refractory epilepsy; Stereotactic guidance.

Publication types

Review

MeSH terms

Brain Mapping / methods*
Epilepsy / pathology
Epilepsy / surgery*
Humans
Magnetic Resonance Imaging*
Minimally Invasive Surgical Procedures / methods*
Neurosurgical Procedures / methods*
Stereotaxic Techniques*
Treatment Outcome