Alveolar Capillary Dysplasia as a Cause of Persistent Pulmonary Hypertension

Abdul Razak; Pankaj Kumar Mohanty; N Karthik Nagesh

doi:10.1007/s13312-015-0759-y

Alveolar Capillary Dysplasia as a Cause of Persistent Pulmonary Hypertension

Indian Pediatr. 2015 Nov;52(11):984-6. doi: 10.1007/s13312-015-0759-y.

Authors

Abdul Razak¹, Pankaj Kumar Mohanty, N Karthik Nagesh

Affiliation

¹ Department of Neonatology, Manipal Hospital. Bangalore, India. Correspondence to: Dr N Karthik Nagesh, Head, Department of Neonatology, Manipal Group of Hospitals, Bangalore, India. drkarthiknagesh@gmail.com.

PMID: 26615352
DOI: 10.1007/s13312-015-0759-y

Abstract

Background: Persistent pulmonary hypertension (PPHN) in a term or late preterm has varied etiology.

Case characteristics: A late preterm neonate operated for esophageal atresia with tracheo-esophageal fistula was complicated by severe pulmonary hypertension and unable to be weaned off from respiratory support.

Outcome: The neonate expired by 15 weeks of life; diagnosis was made on postmortem lung biopsy.

Message: Alveolarcapillary dysplasia should be considered in a neonate with idiopathic refractory PPHN, if associated with anomalies.

Publication types

Case Reports

MeSH terms

Esophageal Atresia / etiology*
Fatal Outcome
Humans
Infant, Newborn
Male
Persistent Fetal Circulation Syndrome* / complications
Persistent Fetal Circulation Syndrome* / diagnosis
Persistent Fetal Circulation Syndrome* / physiopathology
Pulmonary Alveoli / abnormalities*
Pulmonary Alveoli / physiopathology

Supplementary concepts

Alveolar capillary dysplasia