Surgical management of a giant sternal chondromyxoid fibroma: a case report

J Cardiothorac Surg. 2015 Nov 28:10:178. doi: 10.1186/s13019-015-0370-2.


Background: A primary chondromyxoid fibroma (CMF) arising from sternum is quite uncommon tumor in thoracic surgery. Removal of giant sternal tumors requires extensive resection of the anterior chest wall, and results in deformity and paradoxical movement.

Case presentation: A 40-year-old female presented a progressively enlarging mass of her anterior chest wall. Computed tomography revealed an osteolytic lesion with discrete calcification in the bone marrow of the sternum. The tumor extended across the destroyed cortex to the parietal and visceral soft aspects, involving some of the costal cartilage and most of the sternal body. Partial sternal resection was performed successfully and an individual-specific stainless steel plate was used to reconstruct the anterior chest wall. The early result was good, however, nine months after the first surgery, fractures of plate were found at bilateral plate-clavicular junction. The plate had to be removed, and a titanium mesh was used to reconstruction of the chest wall. The patient has been of disease free for more than 18 month after the second surgery.

Conclusions: Our experience indicated that the individual-specific plate may not be suitable for reconstructing both the anterior chest wall as well as the sternoclavicular joint after subtotal sternum resection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / surgery*
  • Chondroma / diagnosis
  • Chondroma / surgery*
  • Female
  • Fibroma / diagnosis
  • Fibroma / surgery*
  • Humans
  • Neoplasm Staging*
  • Sternotomy / methods*
  • Sternum*
  • Thoracic Neoplasms / diagnosis
  • Thoracic Neoplasms / surgery*
  • Tomography, X-Ray Computed