Overlap of microcystic stromal tumor and primary solid pseudopapillary neoplasm of the ovary

Int J Clin Exp Pathol. 2015 Sep 1;8(9):11792-7. eCollection 2015.

Abstract

Ovarian microcystic stromal tumors (MCSTs) and ovarian primary solid pseudopapillairy neoplasms (SPNs) are rare ovarian tumors, and recently classified as distinctive variant in the stromal category and miscellaneous tumors respectically in 2009 and 2010. Ever since, there were less then 10 MCSTs and ovarian primary SPNs reported in English literatures. Both of them had something in common, including microscopical morphology, immunohistochemical phenotype, even for the tumorigenesis pathway. Hence, is there any possible linkage between them? In addition to a thorough case description, the literature concerning this entity is reviewed and discussed.

Keywords: Ovarian microcystic stromal tumor; primary solid pseudopapillary neoplasm of the ovary; the morphologic and immunohistochemica display.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biopsy
  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Neoplasms, Cystic, Mucinous, and Serous / chemistry
  • Neoplasms, Cystic, Mucinous, and Serous / pathology*
  • Neoplasms, Cystic, Mucinous, and Serous / surgery
  • Ovarian Neoplasms / chemistry
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Phenotype
  • Stromal Cells / chemistry
  • Stromal Cells / pathology*
  • Treatment Outcome

Substances

  • Biomarkers, Tumor