Case Report: An Outbreak of Food-Borne Typhoid Fever Due to Salmonella enterica Serotype Typhi in Japan Reported for the First Time in 16 Years

Am J Trop Med Hyg. 2016 Feb;94(2):289-291. doi: 10.4269/ajtmh.15-0484. Epub 2015 Nov 30.


For the first time in 16 years, a food-borne outbreak of typhoid fever due to Salmonella enterica serotype Typhi was reported in Japan. Seven patients consumed food in an Indian buffet at a restaurant in the center of Tokyo, while one was a Nepali chef in the restaurant, an asymptomatic carrier and the implicated source of this outbreak. The multiple-locus variable-number tandem repeat analysis showed 100% consistency in the genomic sequence for five of the eight cases.

MeSH terms

  • Adult
  • Child
  • Child, Preschool
  • Disease Outbreaks*
  • Female
  • Foodborne Diseases / epidemiology
  • Foodborne Diseases / microbiology*
  • Humans
  • Japan / epidemiology
  • Male
  • Typhoid Fever / drug therapy
  • Typhoid Fever / epidemiology*
  • Young Adult