Measurement of absolute flow rate in vessels using a stereoscopic DSA system

Phys Med Biol. 1989 Jun;34(6):659-71. doi: 10.1088/0031-9155/34/6/002.


We used a stereoscopic digital subtraction angiography (DSA) system to measure absolute blood flow rates in vessels. The magnification factor and the three-dimensional orientation of a selected vessel are obtained from automated analysis of stereoscopic DSA images. The cross-sectional area of the vessel is determined from the vessel diameter, which is measured with an iterative deconvolution technique. The time required for fluid to flow through a selected segment of a vessel is determined from the automated analysis of contrast medium 'time-density' curves. The effectiveness of these combined techniques was demonstrated in measurement of rates of both continuous and pulsatile flow in a vessel phantom, with the actual flow rate calibrated volumetrically or by an electromagnetic flowmeter. We have obtained accuracies in measured flow rates of approximately 5% and 18% for continuous and pulsatile flow respectively.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Angiography / methods*
  • Blood Flow Velocity*
  • Blood Vessels / physiology*
  • Humans
  • Models, Structural
  • Pulsatile Flow
  • Radiographic Image Enhancement
  • Regional Blood Flow
  • Subtraction Technique