Colchicine for cardiovascular medicine

Future Cardiol. 2016 Jan;12(1):9-16. doi: 10.2217/fca.15.59. Epub 2015 Dec 3.


Colchicine is an ancient drug with anti-inflammatory effects especially on neutrophils. These cells are critically involved in pericardial and atherosclerotic plaques inflammation, thus representing a new potential target for new therapies to treat and especially prevent cardiovascular events such as pericarditis, atrial fibrillation triggered by inflammation and ischemic vascular events. The aim of the present review is to briefly review the essential pharmacology and explore potential efficacy and safety of colchicine for new emerging cardiovascular indications.

Keywords: acute coronary syndrome; atrial fibrillation; colchicine; pericarditis; restenosis; stable angina.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / pharmacology*
  • Cardiovascular Diseases / drug therapy*
  • Clinical Trials as Topic
  • Colchicine / pharmacology*
  • Contraindications
  • Humans
  • Off-Label Use


  • Anti-Inflammatory Agents
  • Colchicine