[Leptospirosis frequency and socio-demographic characteristics associated in febrile patients from northern Perú]

Rev Chilena Infectol. 2015 Oct;32(5):530-5. doi: 10.4067/S0716-10182015000600006.
[Article in Spanish]

Abstract

INDRODUCTION: Leptospirosis is a frequent cause of febrile illness around the world, particularly in tropical and subtropical areas such as Perú.

Objective: To estimate the frequency and socio-demographic characteristics associated with leptospirosis in febrile patients in northern Perú.

Materials and methods: A cross sectional study was conducted from January to December 2014 in 143 fever cases admitted to the Hospital Regional Lambayeque, Perú. Structured for socio-demographic information and sanitation questionnaire was used. Serum samples were examined to quantitatively determine the presence of IgM antibodies to leptospira using ELISA IgM.

Results: The frequency was 26.6% (95% CI 19.3 to 33.8) and independently associated features were: be between 20-54 years (OR: 3.36, 95% CI 1.17 to 9, 64), work in agriculture-livestock (OR: 6.15, 95% CI 1.99 to 19.05),contact with animals (OR: 4,13, IC 95%: 1,76-9,65) and consumption of unsafe water(OR: 3,33, IC 95%: 1,49-7,43).

Conclusions: This study reveals a high frequency of leptospirosis among febrile patients from northern Perú. These results indicate the need to investigate routinely leptospirosis in febrile patients, especially those exhibiting risk characteristics.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Antibodies, Bacterial / blood*
  • Cross-Sectional Studies
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Fever / epidemiology*
  • Fever / microbiology
  • Humans
  • Leptospira / immunology*
  • Leptospirosis / diagnosis
  • Leptospirosis / epidemiology*
  • Male
  • Middle Aged
  • Peru / epidemiology
  • Risk Factors
  • Socioeconomic Factors
  • Young Adult

Substances

  • Antibodies, Bacterial