A New Golden Age of Natural Products Drug Discovery

Cell. 2015 Dec 3;163(6):1297-300. doi: 10.1016/j.cell.2015.11.031.

Abstract

The 2015 Nobel Prize in Physiology or Medicine has been awarded to William C. Campbell, Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies that revolutionized the treatment of devastating parasite diseases. With the recent technological advances, a New Golden Age of natural products drug discovery is dawning.

Publication types

  • Biography
  • Historical Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Artemisinins / chemistry
  • Artemisinins / therapeutic use
  • Drug Discovery*
  • History of Medicine
  • History, 21st Century
  • Ivermectin / analogs & derivatives
  • Ivermectin / chemistry
  • Ivermectin / therapeutic use
  • Nobel Prize*
  • Parasitic Diseases / drug therapy*
  • Physiology / history

Substances

  • Artemisinins
  • Ivermectin
  • avermectin
  • artemisinine

Personal name as subject

  • William C Campbell
  • Satoshi Omura
  • Youyou Tu