Management of recurrence after initial surgery for malignant pleural mesothelioma: a mini-review

Future Oncol. 2015;11(24 Suppl):23-7. doi: 10.2217/fon.15.312.


Recurrence after surgery in the multimodality therapy for malignant pleural mesothelioma is a common problem. As the majority of patients experience not only local but also distant metastases, a systemic treatment strategy in addition to local control measures remains necessary. Nevertheless, none of the chemotherapy regimens have achieved clinical success. Local management modalities such as stereotaxic treatments, cryoablation and redo surgery on the other hand have promising results, but provide palliative outcomes.

Keywords: failure; mesothelioma; recurrence; surgery.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy / methods
  • Disease Management
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / therapy*
  • Mesothelioma / drug therapy*
  • Mesothelioma / therapy*
  • Mesothelioma, Malignant
  • Neoplasm Recurrence, Local / drug therapy*
  • Neoplasm Recurrence, Local / therapy*
  • Pleural Neoplasms / drug therapy*
  • Pleural Neoplasms / therapy*