Endogenous factors contributing to prosthetic device infections

Infect Dis Clin North Am. 1989 Jun;3(2):199-209.


Although there is a direct association between the tissue reactivity of implants and their ability to potentiate infection, bacterial slime production and adherence to implant surfaces (generation of the biofilm) appear to play a primary role in the pathogenesis of most prosthesis infections.

Publication types

  • Review

MeSH terms

  • Bacteria / metabolism
  • Bacterial Adhesion
  • Bacterial Infections / etiology*
  • Foreign-Body Reaction / etiology*
  • Glycoproteins / biosynthesis
  • Humans
  • Neutrophils / immunology
  • Polysaccharides / biosynthesis
  • Prostheses and Implants / adverse effects*


  • Glycoproteins
  • Polysaccharides