Aplasia cutis congenita: A case report and literature review

Exp Ther Med. 2015 Nov;10(5):1893-1895. doi: 10.3892/etm.2015.2737. Epub 2015 Sep 9.


Aplasia cutis congenita (ACC) is a rare condition with an unclear pathogenic mechanism, although the condition has been suggested to occur as a result of the disrupted development or degeneration of skin in utero. ACC associated with fetus papyraceus has been described in numerous studies. Although there have been several reports of ACC, surgical treatment of ACC using the head as a site of donor skin is rarely reported. The present study describes the case of a 1-week-old patient with ACC that was healed by skin grafting, using the scalp as the donor site. The outcome of the procedure showed that the use of the scalp as a donor skin site for grafting is an effective treatment for large and deep ACC lesions arising on sites other than the head.

Keywords: aplasia cutis congenita; infant; skin graft; treatment.