Towards Multidisciplinary HIV-Cure Research: Integrating Social Science with Biomedical Research

Trends Microbiol. 2016 Jan;24(1):5-11. doi: 10.1016/j.tim.2015.10.011. Epub 2015 Nov 28.


The quest for a cure for HIV remains a timely and key challenge for the HIV research community. Despite significant scientific advances, current HIV therapy regimens do not completely eliminate the negative impact of HIV on the immune system; and the economic impact of treating all people infected with HIV globally, for the duration of their lifetimes, presents significant challenges. This article discusses, from a multidisciplinary approach, critical social, behavioral, ethical, and economic issues permeating the HIV-cure research agenda. As part of a search for an HIV cure, both the perspective of patients/participants and clinical researchers should be taken into account. In addition, continued efforts should be made to involve and educate the broader community.

Keywords: HIV cure; cost-effectiveness; ethics; multidisciplinary; public understanding of science.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acquired Immunodeficiency Syndrome / therapy
  • Biomedical Research / economics
  • Biomedical Research / ethics
  • Biomedical Research / methods*
  • Biomedical Research / trends
  • Clinical Trials as Topic / economics
  • Clinical Trials as Topic / ethics
  • Clinical Trials as Topic / methods
  • Cooperative Behavior
  • Cost-Benefit Analysis
  • HIV Infections / therapy*
  • Humans
  • Interdisciplinary Communication
  • Remission Induction
  • Social Sciences / economics
  • Social Sciences / ethics
  • Social Sciences / methods*
  • Social Sciences / trends