The effectiveness of neurolytic block of sphenopalatine ganglion using zygomatic approach for the management of trigeminal neuropathy

Neurol Neurochir Pol. 2015;49(6):389-94. doi: 10.1016/j.pjnns.2015.08.010. Epub 2015 Sep 19.


This study was performed to present the outcomes of trigeminal neuropathy management with the application of neurolytic block of sphenopalatine ganglion. This type of procedure is used in cases where pain is not well controlled with medical treatment. Twenty patients were treated with sphenopalatine ganglion neurolysis after their response to pharmacological management was not satisfactory. Significant pain relief was experienced by all but one patient and they were able to reduce or stop their pain medication. The time of pain relief was between a few months and 9 years during the study period. Number of procedures implemented varied as some of the patients have been under the care of our Pain Clinic for as long as 18 years, satisfied with this type of management and willing to have the procedure repeated if necessary. It appears that neurolytic block of sphenopalatine ganglion is effective enough and may be an option worth further consideration in battling the pain associated with trigeminal neuropathy.

Keywords: Neurolytic block; Neuropathic pain; Sphenopalatine ganglion; Trigeminal neuropathy.

MeSH terms

  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neuralgia / drug therapy*
  • Pain Management
  • Sphenopalatine Ganglion Block / methods*
  • Treatment Outcome
  • Trigeminal Nerve Diseases / drug therapy*
  • Zygoma*