Neurobiology: Setting the Set Point for Neural Homeostasis

Torrey L S Truszkowski; Carlos D Aizenman

doi:10.1016/j.cub.2015.10.021

Neurobiology: Setting the Set Point for Neural Homeostasis

Curr Biol. 2015 Dec 7;25(23):R1132-3. doi: 10.1016/j.cub.2015.10.021.

Authors

Torrey L S Truszkowski¹, Carlos D Aizenman²

Affiliations

¹ Department of Neuroscience, Brown University, Providence, RI 02912, USA.
² Department of Neuroscience, Brown University, Providence, RI 02912, USA. Electronic address: Carlos_Aizenman@brown.edu.

PMID: 26654372
DOI: 10.1016/j.cub.2015.10.021

Abstract

Neural homeostasis allows neural networks to maintain a dynamic range around a given set point. How this set point is determined remains unknown. New evidence shows that alterations of activity during a critical developmental period can alter the homeostatic set point, resulting in epilepsy-like activity.

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MeSH terms

Epilepsy
Homeostasis*
Humans
Neural Networks, Computer
Neurobiology*