Vibrio bivalvicida sp. nov., a novel larval pathogen for bivalve molluscs reared in a hatchery

Syst Appl Microbiol. 2016 Feb;39(1):8-13. doi: 10.1016/j.syapm.2015.10.006. Epub 2015 Nov 22.

Abstract

Three isolates were obtained from cultures of carpet shell clam (Ruditapes decussatus) reared in a bivalve hatchery (Galicia, NW Spain) from different sources: healthy broodstock, moribund larvae and the seawater corresponding to the larval tank. All isolates were studied by a polyphasic approach, including a phylogenetic analysis based on concatenated sequences of the five housekeeping genes ftsZ, gyrB, pyrH, recA and rpoA. The analysis supported their inclusion in the Orientalis clade of the genus Vibrio, and they formed a tight group separated from the closest relatives: Vibrio tubiashii subsp. europaensis, Vibrio tubiashii subsp. tubiashii and Vibrio orientalis. The percentages of genomic resemblance, including average nucleotide identity, DNA-DNA hybridization and in silico genome-to-genome comparison, between the type strain and the closest relatives were below values for species delineation and confirmed the taxonomic position of the new species, which could be differentiated from the related taxa on the basis of several phenotypic and chemotaxonomic features, including FAME and MALDI-TOF-MS. The pathogenicity of the new species was demonstrated in larvae of R. decussatus, Ruditapes philippinarum, Ostrea edulis and Donax trunculus. The results demonstrated that the strains analyzed represented a novel species in the Orientalis clade of the genus Vibrio, for which the name Vibrio bivalvicida sp. nov. is proposed, with 605(T) (= CECT 8855(T)=CAIM 1904(T)) designated as the type strain.

Keywords: ANI; Bivalve hatchery; DDH; Larval pathogen; Orientalis clade; Vibrio bivalvicida sp. nov..

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aquaculture*
  • Bacterial Proteins / genetics
  • Bivalvia / microbiology*
  • Cytoskeletal Proteins / genetics
  • DNA Gyrase / genetics
  • DNA Probes
  • DNA-Directed RNA Polymerases / genetics
  • Genome, Bacterial / genetics
  • Larva / microbiology
  • Rec A Recombinases / genetics
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Transferases / genetics
  • Vibrio / classification*
  • Vibrio / genetics
  • Vibrio / pathogenicity*

Substances

  • Bacterial Proteins
  • Cytoskeletal Proteins
  • DNA Probes
  • FtsZ protein, Bacteria
  • Transferases
  • Rec A Recombinases
  • DNA-Directed RNA Polymerases
  • RNA polymerase alpha subunit
  • DNA Gyrase