Bringing genetic background into focus

Nat Rev Genet. 2016 Feb;17(2):63-4. doi: 10.1038/nrg.2015.9. Epub 2015 Dec 14.


Researchers should embrace differences in genetic background to build richer disease models that more accurately reflect the level of variation in the human population, posits Clement Chow.

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Drosophila / genetics
  • Genetic Background*
  • Genetic Variation*
  • Genetics, Medical / methods*
  • Humans
  • Mice, Inbred C57BL
  • Mutation