Omeprazole inhibits melanin biosynthesis in melan-a cells and zebrafish

Exp Dermatol. 2016 Mar;25(3):239-41. doi: 10.1111/exd.12915. Epub 2016 Feb 10.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Arbutin / chemistry
  • Cell Line
  • Copper / chemistry
  • Dose-Response Relationship, Drug
  • Gene Expression Regulation, Developmental / drug effects
  • Melanins / biosynthesis*
  • Melanocytes / drug effects*
  • Mice
  • Microphthalmia-Associated Transcription Factor / metabolism
  • Omeprazole / chemistry*
  • Pigmentation / drug effects
  • Proton Pump Inhibitors / chemistry
  • Skin / drug effects*
  • Tyrosine / chemistry
  • Zebrafish

Substances

  • Melanins
  • Microphthalmia-Associated Transcription Factor
  • Proton Pump Inhibitors
  • Tyrosine
  • Copper
  • Arbutin
  • Omeprazole