A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET
- PMID: 26661391
- DOI: 10.1039/c5cc08060f
A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET
Abstract
We present here a signal-on fluorescence biosensor for highly sensitive and specific detection of tumor cells with a split aptamer based on fluorescence resonance energy transfer (FRET). This sensor holds considerable potential for simple, rapid, sensitive and specific tumor cell detection in early clinical diagnosis.
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