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. 2016 Jan 28;52(8):1590-3.
doi: 10.1039/c5cc08060f. Epub 2015 Dec 10.

A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET

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A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET

Baoyin Yuan et al. Chem Commun (Camb). .

Abstract

We present here a signal-on fluorescence biosensor for highly sensitive and specific detection of tumor cells with a split aptamer based on fluorescence resonance energy transfer (FRET). This sensor holds considerable potential for simple, rapid, sensitive and specific tumor cell detection in early clinical diagnosis.

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