Probiotics in man and animals

J Appl Bacteriol. 1989 May;66(5):365-78.


There is good evidence that the complex microbial flora present in the gastrointestinal tract of all warm-blooded animals is effective in providing resistance to disease. However, the composition of this protective flora can be altered by dietary and environmental influences, making the host animal susceptible to disease and/or reducing its efficiency of food utilization. What we are doing with the probiotic treatments is re-establishing the natural condition which exists in the wild animal but which has been disrupted by modern trends in conditions used for rearing young animals, including human babies, and in modern approaches to nutrition and disease therapy. These are all areas where the gut flora can be altered for the worse and where, by the administration of probiotics, the natural balance of the gut microflora can be restored and the animal returned to its normal nutrition, growth and health status.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / standards
  • Anti-Bacterial Agents / therapeutic use*
  • Bacteria / drug effects
  • Bacteria / growth & development*
  • Bacterial Infections / drug therapy*
  • Digestive System / microbiology*
  • Growth Substances / pharmacology
  • Growth Substances / standards
  • Growth Substances / therapeutic use*
  • Humans
  • Quality Control


  • Anti-Bacterial Agents
  • Growth Substances