Expanding the computational toolbox for interrogating cancer kinomes

Pharmacogenomics. 2016;17(2):95-7. doi: 10.2217/pgs.15.154. Epub 2015 Dec 15.
No abstract available

Keywords: Kinase Addiction Ranker; cancer kinome; kinase dependency; kinase inhibitor connectivity map; targeted therapies.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Computational Biology / methods*
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / enzymology*
  • Oncogenes
  • Protein Kinase Inhibitors / therapeutic use
  • Protein Kinases / genetics*
  • Protein Kinases / metabolism

Substances

  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • Protein Kinases