[VITAMIN D AND ITS RELATION WITH THE ANATOMICAL LOCATION OF HIP FRACTURE IN CHILEAN OLDER ADULTS HOSPITALIZED]

Nutr Hosp. 2015 Dec 1;32(6):2777-82. doi: 10.3305/nh.2015.32.6.9795.
[Article in Spanish]

Abstract

Introduction: in older adults, deficit of Vitamin D and hip fractures are common. There exists relationships between both conditions, and it have been shown that supplementation of Vitamin D improve prognosis of hip fractures. In the case of Chile, information about relationship between Vitamin D and hip fractures is scarce.

Objective: quantify plasma levels of vitamin D and relate them to the anatomical location of hip fracture.

Methods: cross-sectional study. 222 Chilean adults ≥60 years, hospitalized for hip fracture between June, 2014 and June, 2015. We use data of medical records about gender, age, seasonality and anatomical location of hip fracture (intra and extracapsular). We measure plasmatic levels of Vitamin D (PLVD) and glomerular filtration rate (GFR) (MDRD-6). Kolmogorov-Smirnov test and non-parametric test were used. For determine relations between PLVD and anatomical location we use linear regression.

Results: there was a predominance of women (80.6%). The average age was 80.7 years (SD=7.8). Intracapsular hip fractures were 43.2%. 80% of the sample presents Vitamin D in deficitary levels (n = 180). PLVD average was 13.3 ng/cc (SD=6.7), in subjects with intracapsular fractures were significantly lower (p<0.001).

Conclusions: PLVD in subjects with hip fracture should be monitored, as there are differences according to anatomical location of the fracture. This precedent could favor the treatment and recovery of subjects presenting for the first time hip fracture.

Introducción: en los adultos mayores son frecuentes el deficit de vitamina D y las fracturas de cadera (FC). Existe relacion entre ambas condiciones, demostrandose que la suplementacion de vitamina D mejora el pronostico de las FC. En el caso de Chile, existe escasa informacion sobre la relacion entre vitamina D y FC. Objetivo: cuantificar los niveles plasmaticos de vitamina D (NPVD) y relacionarlos con la ubicacion anatomica de la FC. Métodos: estudio transversal. 222 adultos mayores chilenos ≥60 anos hospitalizados por FC entre junio de 2014 y junio de 2015. Se utilizaron los datos de ficha clinica de genero, edad, estacionalidad y ubicacion anatomica (FIC = intra, FEC = extracapsular) de la FC. Se midio NPVD y velocidad de filtrado glomerular (VFG) (MDRD- 6). Se utilizaron la prueba de Kolmogorov-Smirnov y pruebas no parametricas. Para determinar la relacion entre NPVD y el tipo de fractura se uso regresion lineal. Resultados: hubo predominio de mujeres (80,6%), la edad promedio fue 80,7 anos (DE=7,8) y se encontro 43,2% de FIC. Los NPVD promedio fueron 13,3 ng/cc (DE=6,7); los sujetos con FIC tienen 4,52 ng/cc menos de vitamina D que aquellos con FEC (p.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chile / epidemiology
  • Cross-Sectional Studies
  • Female
  • Hip Fractures / epidemiology*
  • Hip Fractures / metabolism*
  • Hip Fractures / pathology
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Vitamin D / blood
  • Vitamin D / metabolism*
  • Vitamin D Deficiency / epidemiology*
  • Vitamin D Deficiency / metabolism*
  • Vitamin D Deficiency / pathology

Substances

  • Vitamin D