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. 2015 Oct;10(10):1641-2.

Antimycobacterial Natural Products from Endophytes of the Medicinal Plant Aralia nudicaulis

  • PMID: 26669092

Antimycobacterial Natural Products from Endophytes of the Medicinal Plant Aralia nudicaulis

Haoxin Li et al. Nat Prod Commun. 2015 Oct.

Abstract

Antimycobacterial extracts of a Penicillium sp. (isolate HL4-159-41B) and a Coniothyrium sp. (isolate HL6-097-027B) isolated from the rhizomes of the Canadian medicinal plant Aralia nudicaulis were found to contain palitantin (1) and botrallin (2), craterellin C (3), mycosporulone (4), spiromassaritone (5), and massarigenin D (6) respectively. Bioassays against Mycobacterium tuberculosis H37Ra revealed that 1 - 4 possess moderate antimycobacterial activity.

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