Sesquiterpenes from Essential Oils and Anti-Inflammatory Activity

Nat Prod Commun. 2015 Oct;10(10):1767-74.


This review is aimed at presenting relevant information on the therapeutic potential of essential oil sesquiterpenes with anti-inflammatory activity. The data reviewed provide a basis for seeking new anti-inflammatory drugs from natural products that do not exhibit the undesirable side effects often displayed by anti-inflammatory drugs. In this review the experimental models, possible mechanisms of action, and chemical structures of 12 sesquiterpenes are presented.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology*
  • Molecular Structure
  • Oils, Volatile / chemistry*
  • Plant Oils / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / pharmacology*


  • Anti-Inflammatory Agents
  • Oils, Volatile
  • Plant Oils
  • Sesquiterpenes