canSAR: an updated cancer research and drug discovery knowledgebase

Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15.


canSAR ( is a publicly available, multidisciplinary, cancer-focused knowledgebase developed to support cancer translational research and drug discovery. canSAR integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and druggability data. canSAR is widely used to rapidly access information and help interpret experimental data in a translational and drug discovery context. Here we describe major enhancements to canSAR including new data, improved search and browsing capabilities, new disease and cancer cell line summaries and new and enhanced batch analysis tools.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Cell Line, Tumor
  • Clinical Trials as Topic
  • Drug Discovery*
  • Gene Expression
  • Humans
  • Knowledge Bases*
  • Neoplasm Proteins / chemistry
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism
  • Neoplasms / genetics
  • Neoplasms / metabolism*


  • Antineoplastic Agents
  • Neoplasm Proteins