Abstract
The authors report a new case of Townes-Brocks syndrome with cardiac defect, ossicular anomalies and dominant transmission. The intrafamilial variability of the phenotype and the difficulty of diagnosis in isolated cases are underlined.
MeSH terms
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Anus, Imperforate / genetics*
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Child
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Ear Ossicles / abnormalities
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Ear, External / abnormalities*
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Female
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Fingers / abnormalities*
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Hearing Loss, Sensorineural / genetics*
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Heart Septal Defects, Ventricular / genetics
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Humans
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Pedigree
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Phenotype
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Syndrome
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Thumb / abnormalities