Mechanisms And Prevention Of TAVI-Related Cerebrovascular Events

Curr Pharm Des. 2016;22(13):1879-87. doi: 10.2174/1381612822666151217122610.


Introduction of transcatheter aortic valve implantation (TAVI) has resulted in a paradigm shift in the treatment of patients with high risk or inoperable severe aortic stenosis. This article aims to comprehensively review the mechanisms of neurological injury per se, the read-outs of cerebrovascular events, and strategies currently used to predict and prevent stroke in transcatheter aortic valve implantation.

Publication types

  • Review

MeSH terms

  • Aortic Valve Stenosis / surgery
  • Cardiac Catheterization*
  • Humans
  • Reperfusion Injury / prevention & control*
  • Transcatheter Aortic Valve Replacement / adverse effects*