Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Nov;273(11):3511-3531.
doi: 10.1007/s00405-015-3855-7. Epub 2015 Dec 19.

Salivary Acinic Cell Carcinoma: Reappraisal and Update

Affiliations
Review

Salivary Acinic Cell Carcinoma: Reappraisal and Update

V Vander Poorten et al. Eur Arch Otorhinolaryngol. .

Abstract

Epidemiologic and clinicopathologic features, therapeutic strategies, and prognosis for acinic cell carcinoma of the major and minor salivary glands are critically reviewed. We explore histopathologic, histochemical, electron microscopic and immunohistochemical aspects and discuss histologic grading, histogenesis, animal models, and genetic events. In the context of possible diagnostic difficulties, the relationship to mammary analog secretory carcinoma is probed and a classification is suggested. Areas of controversy or uncertainty, which may benefit from further investigations, are also highlighted.

Keywords: Acinic cell carcinoma; Mammary analog secretory carcinoma; Pathology; Prognosis; Salivary glands; Therapy.

Similar articles

See all similar articles

Cited by 10 articles

See all "Cited by" articles

References

    1. Int Forum Allergy Rhinol. 2014 Jun;4(6):507-11 - PubMed
    1. Cancer Cytopathol. 2013 May;121(5):228-33 - PubMed
    1. Oral Oncol. 2015 Jul;51(7):652-61 - PubMed
    1. Am J Clin Pathol. 2003 Jun;119(6):801-6 - PubMed
    1. J Neurol Surg B Skull Base. 2012 Dec;73(6):371-8 - PubMed

LinkOut - more resources

Feedback