Vitamin C as Cancer Destroyer, Investigating Sulfhydration, and the Variability in CFTR Interactome

Chem Biol. 2015 Dec 17;22(12):1575-6. doi: 10.1016/j.chembiol.2015.12.002.

Abstract

Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights are a snapshot of interesting research done across the field of chemical biology. Our December 2015 selection includes an insight into how vitamin C destroys cancer cells, a new method that makes possible the investigatation of sulfhydration, and the mapping of the CFTR interactome and how it depends on the environmental conditions and differs between wild-type and disease-causing mutant.

Publication types

  • Comment

MeSH terms

  • Animals
  • Ascorbic Acid / therapeutic use*
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / genetics*
  • Female
  • Humans
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins B-raf / genetics*
  • ras Proteins / genetics*

Substances

  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins B-raf
  • ras Proteins
  • Ascorbic Acid