GMP synthesis of carbon-14 labelled substances

J Labelled Comp Radiopharm. 2016 May 30;59(6):233-7. doi: 10.1002/jlcr.3364. Epub 2015 Dec 23.

Authors

Crist N Filer¹, Mario P Maniscalco¹, Sandra L Thayer¹

Affiliation

¹ PerkinElmer Health Sciences, Inc., 940 Winter Street, Waltham, MA, 02451, USA.

PMID: 26695715
DOI: 10.1002/jlcr.3364

Abstract

This review discusses the process of preparing and analyzing carbon-14 labelled substances under good manufacturing practice.

Keywords: ADME; GMP; carbon-14.

Copyright © 2015 John Wiley & Sons, Ltd.

Publication types

Review

MeSH terms

Carbon Radioisotopes / chemistry*
Chemistry Techniques, Synthetic / methods*
Isotope Labeling

Substances

Carbon Radioisotopes