Safety and Feasibility of Transradial Access for Visceral Interventions in Patients with Thrombocytopenia

Cardiovasc Intervent Radiol. 2016 May;39(5):676-682. doi: 10.1007/s00270-015-1264-3. Epub 2015 Dec 22.


Purpose: Transradial access (TRA) has shown lower morbidity and decreased bleeding complications compared to transfemoral access. This study evaluates the safety and feasibility of TRA in thrombocytopenic patients undergoing visceral interventions.

Methods and materials: Patients who underwent visceral interventions via the radial artery with platelet count less than or equal to 50,000/µL were included in the study. Outcome variables included technical success, access site, bleeding, transfusion, and neurological complications.

Results: From July 1, 2012, to May 31, 2015, a total of 1353 peripheral interventions via TRA were performed, of which 85 procedures were performed in 64 patients (mean age 62.2 years) with a platelet count <50,000/µL (median 39,000/µL). Interventions included chemoembolization (n = 46), selective internal radiation therapy (n = 30), and visceral embolization (n = 9). Technical success was 97.6% with two cases of severe vessel spasm requiring ipsilateral femoral crossover. There was no major access site, bleeding, or neurological adverse events at 30 days. Minor access site hematomas occurred in five cases (5.9%) and were treated conservatively in all cases. Pre-procedural platelet transfusions were administered in 23 (27.1%) cases. There was no statistically significant difference in access site or bleeding complications between the transfused and nontransfused groups.

Conclusions: Transradial visceral interventions in patients with thrombocytopenia are both feasible and safe, possibly without the need for platelet transfusions.

Keywords: Clinical practice; Organ, Intra-arterial; Specialty, Arterial intervention; Specialty, Artery; Subspecialty/technique.

MeSH terms

  • Aged
  • Brachytherapy / methods*
  • Catheterization, Peripheral / adverse effects*
  • Embolization, Therapeutic / methods*
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radial Artery*
  • Thrombocytopenia / complications*
  • Treatment Outcome