Rubus occidentalis: The black raspberry--its potential in the prevention of cancer

Nutr Cancer. 2016;68(1):18-28. doi: 10.1080/01635581.2016.1115095. Epub 2015 Dec 23.


Rubus occidentalis is a black-fruited raspberry originating from North America. Its popularity and demand has been growing over the years, as studies outline its high anthocyanin and ellagitannin content and significance for human health. Interaction between chemical composition and pharmacological activity, mechanisms of action at cellular and molecular levels are all active areas of study. The vast majority of research concerning black raspberries is focused on chemoprevention and anticancer effects. This review summarizes the data on chemical composition and anticancer activity of black raspberry fruits throughout the years.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anthocyanins / analysis
  • Antioxidants / pharmacology
  • Clinical Trials as Topic
  • Fruit / chemistry
  • Humans
  • Neoplasms / prevention & control*
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Reactive Oxygen Species / metabolism
  • Rubus* / chemistry


  • Anthocyanins
  • Antioxidants
  • Plant Extracts
  • Reactive Oxygen Species