Identification of a Gain-Of-Function STAT3 Mutation (p.Y640F) in Lymphocytic Variant Hypereosinophilic Syndrome

Blood. 2016 Feb 18;127(7):948-51. doi: 10.1182/blood-2015-06-654277. Epub 2015 Dec 23.

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amino Acid Substitution
  • Female
  • Humans
  • Hypereosinophilic Syndrome / genetics*
  • Hypereosinophilic Syndrome / pathology
  • Mutation, Missense*
  • STAT3 Transcription Factor / genetics*

Substances

  • STAT3 Transcription Factor
  • STAT3 protein, human