Presence of an HO-1 expression threshold in renal glomeruli

Maria G Detsika; Vassileios Atsaves; Apostolos Papalois; Elias A Lianos

doi:10.1016/j.dib.2015.11.001

Presence of an HO-1 expression threshold in renal glomeruli

Data Brief. 2015 Nov 10:5:921-5. doi: 10.1016/j.dib.2015.11.001. eCollection 2015 Dec.

Authors

Maria G Detsika¹, Vassileios Atsaves¹, Apostolos Papalois², Elias A Lianos³

Affiliations

¹ 1st Department of Critical Care Medicine & Pulmonary Services, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
² Research and Experimental center of ELPEN Pharmaceuticals, Athens, Greece.
³ 1st Department of Critical Care Medicine & Pulmonary Services, National and Kapodistrian University of Athens School of Medicine, Athens, Greece ; Division of Nephrology, Department of Medicine, Robert Wood Johnson Medical School, Rutgers Biomedical and Health Sciences, New Brunswick, NJ, United States.

Abstract

This article reports data describing HO-1 expression patterns of heme oxygenase (HO)-1 in isolated rat glomeruli and in cultured glomerular epithelial cells (GEC) in response to its natural substrate heme. Qualitative and quantitative data are presented to support presence of a HO-1 expression threshold in glomeruli but not in GEC. Interpretation of our data and further insight into HO-1 expression pattern in glomeruli may be found in 'HO-1 expression control in the rat glomerulus' [1].

Keywords: Glomeruli; Heme oxygenase; Kidney.