Periodontitis and osteoporosis

Neuro Endocrinol Lett. 2015;36(5):401-6.


Today's knowledge and studies show a firm correlation between osteoporosis and periodontitis, particularly in postmenopausal women. This review study deals with epidemiological and etiopathogenetic association between chronic periodontitis and an osteoporosis. A special emphasis is put on explanation of possible relations between a premature tooth loss and decrease of length and density of jaw bones, particularly their alveolar prolongations. The second part of the paper deals with principles of treatment in patients suffering of osteoporosis. Osteoporosis reduces density of jaw bones and decreases a number of teeth in jaws, but it does not affect other clinical signs and markers of periodontitis such as inflammation, bleeding and the depth of periodontal pockets and microbial plaque.

Publication types

  • Review

MeSH terms

  • Bone Density Conservation Agents / therapeutic use
  • Estrogen Replacement Therapy / methods
  • Female
  • Humans
  • Jaw / metabolism
  • Male
  • Osteoporosis / drug therapy
  • Osteoporosis / epidemiology
  • Osteoporosis / metabolism
  • Osteoporosis, Postmenopausal / drug therapy
  • Osteoporosis, Postmenopausal / epidemiology*
  • Osteoporosis, Postmenopausal / metabolism
  • Periodontitis / epidemiology*
  • Periodontitis / metabolism


  • Bone Density Conservation Agents