Rate of Major Anesthetic-Related Outcomes in the Intraoperative and Immediate Postoperative Period After Cardiac Surgery

J Cardiothorac Vasc Anesth. 2016 Apr;30(2):338-44. doi: 10.1053/j.jvca.2015.08.006. Epub 2015 Aug 10.


Objectives: To examine anesthesia-centered outcomes in a large cohort of patients undergoing coronary artery bypass grafting (CABG) or valvular heart surgery.

Design: A retrospective study with univariate and multivariate logistic regression to identify independent predictors for mortality.

Setting: Diverse setting including university, small, medium, and large community hospitals.

Participants: All patients undergoing CABG or valve surgery in the National Anesthesia Clinical Outcomes Registry (NACOR) from the Anesthesia Quality Institute.

Interventions: None.

Measurements and main results: Common anesthesia-centered outcomes including arrhythmia, cardiac arrest, death, hemodynamic instability, hypotension, inadequate pain control, nausea/vomiting, seizure, stroke, reintubation and transfusion were reported. All outcomes, consistent with NACOR data entry, were defined as occurring intraoperatively or during phase I or II recovery in the PACU. Death occurred in 0.15% of CABGs and 0.23% of valve surgeries. Age less than 18, American Society of Anesthesiologists physical status (ASA PS) classification of 5, and mean case duration greater than 6 hours were associated with increased mortality (p<0.05). The presence of a board-certified anesthesiologist was associated with decreased odds for mortality.

Conclusions: Death was a rare outcome in this cohort, reflecting the infrequent occurrence of intraoperative or immediate postoperative death. The presence of a board-certified anesthesiologist represented a modifiable risk factor for reducing mortality risk.

Keywords: CABG; anesthesiology; cardiac surgery; mortality; outcomes; valve surgery.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anesthesia / adverse effects*
  • Anesthesia / mortality*
  • Anesthesiologists
  • Cardiac Surgical Procedures / mortality*
  • Cohort Studies
  • Coronary Artery Bypass
  • Female
  • Heart Valves / surgery
  • Hospital Mortality
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications / mortality*
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult